I always wanted to try it out so I borrowed one from a buddy. It is like HoN's controls were made for this thing. Very comfortable and everything you need can be mapped and keyed on it. From buying to controlling minions and courier it works well.
I got used to it immediately because it is just like a keyboard; only you don't have to reach as far for different keys.
So if you wanted to try this for HoN please do you will not be let down. Not needed but if you have cash to blow?