1. Place item tooltip closer to the item shop, so when i scroll over the item, I don't have to look at bottom right corner (i play on 1920 X 1200) so lotta distance to cover..
2. I think its been suggested before, the item shop is too big compared to the UI, item shop needs to be MUCH smaller, in line with the size of the current UI, and this would remove cluster on screen, more appealing.
Also if you look at LoL beta, you could probably copy that item shop format, it would be REALLY efficient and nice to look at.. DEFINITE improvement to DOTA and HoN