Brief Description: HoN does not remember the matchmaking regions you selected if you quit the application, then launch it again.
How to Replicate:
1. Open HoN
2. Select preffered region(s) under Matchmaking
3. Quit HoN
4. Open HoN
5. Open Matchmaking to see you have to select the region(s) again
Console.log or Match ID: Not applicable.
I am sure this is not intended.
There is a mod that fixes this but that doesn't mean it should't function like this by default.